Olfactomedin 3 antibody

Catalog No. ABIN7130495

Product Details anti-Olfactomedin 3 Antibody

Target: Olfactomedin 3 (OLFM3)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Olfactomedin 3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human OLFM3

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, WB:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for Olfactomedin 3

Target: Olfactomedin 3 (OLFM3)

Alternative Name: OLFM3 (OLFM3 Products)

Background:

Background: OLFM3 (olfactomedin 3), also known as NOE3, is a 478 amino acid protein that interacts with myocilin. Myocilin is an extracellular protein that plays a key role in the actomyosin system and is responsible for controlling intraocular pressure. OLFM3 is a secreted protein that contains an olfactomedin-like (OLF) domain, an approximately 260 amino acid motif commonly found in secreted glycoproteins. OLFM3 localizes to the Golgi apparatus of the cell and is highly expressed in both eye and brain tissue. Mutations in the gene that encodes OLFM3 may cause severe glaucoma, a condition in which increased intraocular pressure within the eyeball causes loss of eye sight.

Aliases: OLFM3 antibody, NOE3 antibody, UNQ1924/PRO4399 antibody, Noelin-3 antibody, Olfactomedin-3 antibody, Optimedin antibody

UniProt: Q96PB7