MPZ antibody

Catalog No. ABIN7130256

Product Details anti-MPZ Antibody

Target: MPZ (Myelin Protein Zero (MPZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPZ antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Cross-Reactivity: Human, Mouse, Rat

Purification: Antigen affinity purification

Immunogen: Fusion protein of Human MPZ

Isotype: IgG

Application Details

Application Notes: ELISA:1:1000-1:2000, IHC:1:5-1:20,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for MPZ

Target: MPZ (Myelin Protein Zero (MPZ))

Alternative Name: MPZ (MPZ Products)

Synonyms: CHM antibody, CMT1 antibody, CMT1B antibody, CMT2I antibody, CMT2J antibody, CMT4E antibody, CMTDI3 antibody, CMTDID antibody, DSS antibody, HMSNIB antibody, MPP antibody, P0 antibody, Mpp antibody, P-zero antibody, p0 antibody, sc:d0186 antibody, wu:fc04b11 antibody, wu:fi30g06 antibody, zgc:103775 antibody, myelin protein zero antibody, myelin protein zero S homeolog antibody, MPZ antibody, Mpz antibody, mpz antibody, mpz.S antibody

Background:

Background: This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. The P0 glycoprotein, absent in the central nervous system,[1] is a major component of the myelin sheath in peripheral nerves. It comprises a large extracellular N-terminal domain, a single transmembrane (TM) region, and a smaller positively charged intracellular domain.

Aliases: Charcot Marie Tooth neuropathy 1B antibody, CHM antibody, CMT1 antibody, CMT1B antibody, CMT2I antibody, CMT2J antibody, CMT4E antibody, CMTDI3 antibody, CMTDID antibody, DSS antibody, HMSNIB antibody, MPP antibody, MPZ antibody, Myelin peripheral protein antibody, Myelin protein P0 antibody, Myelin protein zero antibody, MYP0_HUMAN antibody, P0 antibody

UniProt: P25189