CNTF Receptor alpha antibody (AA 23-342)

Catalog No. ABIN7128092

Product Details anti-CNTF Receptor alpha Antibody

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Binding Specificity: AA 23-342

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CNTF Receptor alpha antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Cross-Reactivity: Human, Mouse, Rat

Purification: Affinity purification

Immunogen: Fusion protein corresponding to a region derived from 23-342 amino acids of Human ciliary neurotrophic factor receptor

Isotype: IgG

Application Details

Application Notes: WB:1:500-1:2000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Supplied at 0.5 mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.3, 0.05 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for CNTF Receptor alpha

Target: CNTF Receptor alpha (CNTFR) (Ciliary Neurotrophic Factor Receptor (CNTFR))

Alternative Name: CNTFR (CNTFR Products)

Synonyms: CNTFR-alpha antibody, CNTFRALPHA antibody, Cntfralpha antibody, cb549 antibody, fj33e02 antibody, sb:cb549 antibody, wu:fj33e02 antibody, si:bz76a6.1 antibody, si:dz248f2.1 antibody, si:rp71-76a6.1 antibody, ciliary neurotrophic factor receptor antibody, ciliary neurotrophic factor receptor L homeolog antibody, CNTFR antibody, cntfr.L antibody, Cntfr antibody, cntfr antibody

Background:

Background:

This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene.

Aliases: Ciliary neurotrophic factor receptor alpha antibody, Ciliary neurotrophic factor receptor antibody, Ciliary neurotrophic factor receptor subunit alpha antibody, CNTF Receptor alpha antibody, CNTF receptor subunit alpha antibody, CNTFR Alpha antibody, CNTFR antibody, CNTFR-alpha antibody, CNTFR_HUMAN antibody

UniProt: P26992

Pathways: JAK-STAT Signaling, Feeding Behaviour