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Recombinant Topoisomerase II alpha antibody

TOP2A Reactivity: Human WB, IHC, ELISA Host: Rabbit Monoclonal 5B10 unconjugated Recombinant Antibody
Catalog No. ABIN7127851
  • Target See all Topoisomerase II alpha (TOP2A) Antibodies
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 147
    • 61
    • 30
    • 5
    • 5
    • 3
    • 3
    • 3
    • 1
    Human
    Host
    • 110
    • 38
    Rabbit
    Clonality
    • 100
    • 48
    Monoclonal
    Conjugate
    • 73
    • 11
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Topoisomerase II alpha antibody is un-conjugated
    Application
    • 98
    • 58
    • 53
    • 48
    • 23
    • 18
    • 13
    • 7
    • 5
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human, Mouse
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Topoisomerase II alpha
    Clone
    5B10
    Isotype
    IgG
    Top Product
    Discover our top product TOP2A Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
    Alternative Name
    TOP2A (TOP2A Products)
    Synonyms
    TOP2 antibody, TP2A antibody, TOP2A antibody, Top-2 antibody, TOP-2 antibody, F12B17.110 antibody, F12B17_110 antibody, thimet metalloendopeptidase 2 antibody, fc08c07 antibody, wu:fc08c07 antibody, DNA topoisomerase II alpha antibody, DNA topoisomerase II, alpha isozyme antibody, topoisomerase (DNA) II alpha antibody, Zincin-like metalloproteases family protein antibody, TOP2A antibody, Bm1_08705 antibody, Top2a antibody, AT5G10540 antibody, top2a antibody
    Background

    Background: Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity).

    Aliases: DNA topoisomerase 2-alpha (EC 5.99.1.3) (DNA topoisomerase II, alpha isozyme), TOP2A, TOP2

    UniProt
    P11388
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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