Recombinant SUZ12 antibody

Catalog No. ABIN7127832

Product Details anti-SUZ12 Antibody

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SUZ12 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

Cross-Reactivity: Human

Purification: Affinity-chromatography

Immunogen: A synthesized peptide derived from human SUZ12

Clone: 1B10

Isotype: IgG

Application Details

Application Notes: Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IP:1:200-1:1000,

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C,-80 °C

Storage Comment: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Details for SUZ12

Target: SUZ12 (SUZ12 Polycomb Repressive Complex 2 Subunit (SUZ12))

Alternative Name: SUZ12 (SUZ12 Products)

Synonyms: fc31h10 antibody, im:7153578 antibody, si:dkey-10p5.2 antibody, suz12 antibody, wu:fc31h10 antibody, 2610028O16Rik antibody, AI195385 antibody, AU016842 antibody, AW536442 antibody, D11Ertd530e antibody, mKIAA0160 antibody, Xsuz12 antibody, chet9 antibody, jjaz1 antibody, CHET9 antibody, ChET 9 protein antibody, JJAZ1 antibody, suz12l antibody, zgc:100863 antibody, SUZ12 polycomb repressive complex 2b subunit antibody, SUZ12 polycomb repressive complex 2 subunit antibody, suppressor of zeste 12 homolog (Drosophila) antibody, SUZ12 polycomb repressive complex 2 subunit S homeolog antibody, SUZ12 polycomb repressive complex 2a subunit antibody, suz12b antibody, Suz12 antibody, SUZ12 antibody, suz12.S antibody, suz12a antibody

Background:

Background: Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Aliases: Polycomb protein SUZ12 (Chromatin precipitated E2F target 9 protein) (ChET 9 protein) (Joined to JAZF1 protein) (Suppressor of zeste 12 protein homolog), SUZ12, CHET9 JJAZ1 KIAA0160

UniProt: Q15022