Recombinant SSTR2 antibody
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- Target See all SSTR2 Antibodies
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This SSTR2 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (IHC)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Somatostatin Receptor 2
- Clone
- 1C3
- Isotype
- IgG
- Top Product
- Discover our top product SSTR2 Primary Antibody
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- Application Notes
- Recommended dilution: IHC:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SSTR2 (Somatostatin Receptor 2 (SSTR2))
- Alternative Name
- SSTR2 (SSTR2 Products)
- Synonyms
- Smstr2 antibody, SSTR-2 antibody, Smstr-2 antibody, sst2 antibody, SS2R antibody, SSTR2 antibody, MGC80373 antibody, somatostatin receptor 2 antibody, somatostatin receptor 2 L homeolog antibody, SSTR2 antibody, Sstr2 antibody, sstr2.L antibody
- Background
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Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.
Aliases: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1), SSTR2
- UniProt
- P30874
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