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Recombinant SSTR2 antibody

SSTR2 Reactivity: Human ELISA, IHC Host: Rabbit Monoclonal 1C3 unconjugated Recombinant Antibody
Catalog No. ABIN7127820
  • Target See all SSTR2 Antibodies
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 42
    • 25
    • 23
    • 8
    • 7
    • 7
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    Human
    Host
    • 38
    • 4
    Rabbit
    Clonality
    • 38
    • 3
    • 1
    Monoclonal
    Conjugate
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SSTR2 antibody is un-conjugated
    Application
    • 19
    • 12
    • 12
    • 8
    • 6
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Somatostatin Receptor 2
    Clone
    1C3
    Isotype
    IgG
    Top Product
    Discover our top product SSTR2 Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    SSTR2 (Somatostatin Receptor 2 (SSTR2))
    Alternative Name
    SSTR2 (SSTR2 Products)
    Synonyms
    Smstr2 antibody, SSTR-2 antibody, Smstr-2 antibody, sst2 antibody, SS2R antibody, SSTR2 antibody, MGC80373 antibody, somatostatin receptor 2 antibody, somatostatin receptor 2 L homeolog antibody, SSTR2 antibody, Sstr2 antibody, sstr2.L antibody
    Background

    Background: Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization.

    Aliases: Somatostatin receptor type 2 (SS-2-R) (SS2-R) (SS2R) (SRIF-1), SSTR2

    UniProt
    P30874
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