Recombinant SKP2 antibody
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- Target See all SKP2 Antibodies
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This SKP2 antibody is un-conjugated
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Application
- ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human SKP2
- Clone
- 3C11
- Isotype
- IgG
- Top Product
- Discover our top product SKP2 Primary Antibody
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anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 351-424) antibody
SKP2 Reactivity: Human, Mouse, Rat WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (C-Term) antibodySKP2 Reactivity: Human, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-100) antibodySKP2 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reactivity: Human WB, IHC Host: Rabbit Monoclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 43-397) antibodySKP2 Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-424) antibodySKP2 Reactivity: Human WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) antibodySKP2 Reactivity: Human ELISA, IHC, IF Host: Rabbit Monoclonal 6D4 unconjugated Recombinant Antibody
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 156-185) antibodySKP2 Reactivity: Human WB, FACS Host: Rabbit Polyclonal RB19860 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (AA 1-130) antibodySKP2 Reactivity: Human ELISA Host: Mouse Monoclonal 6G9D10 unconjugated
anti-S-Phase Kinase-Associated Protein 2 (SKP2) (N-Term) antibodySKP2 Reactivity: Human, Mouse, Rat WB, IHC, IHC (p), ICC Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IF:1:20-1:200, FC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- SKP2 (S-Phase Kinase-Associated Protein 2 (SKP2))
- Alternative Name
- SKP2 (SKP2 Products)
- Synonyms
- FBXL1 antibody, FBL1 antibody, FLB1 antibody, p45 antibody, RGD1562456 antibody, S-phase kinase-associated protein 2 (p45) antibody, S-phase kinase associated protein 2 antibody, Skp2 antibody, SKP2 antibody
- Background
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Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UBP43, and probably MYC, TOB1 and TAL1. Degradation of TAL1 also requires STUB1. Recognizes CDKN1A in association with CCNE1 or CCNE2 and CDK2. Promotes ubiquitination and destruction of CDH1 in a CK1-Dependent Manner, thereby regulating cell migration.
Aliases: S-phase kinase-associated protein 2 (Cyclin-A/CDK2-associated protein p45) (F-box protein Skp2) (F-box/LRR-repeat protein 1) (p45skp2), SKP2, FBXL1
- UniProt
- Q13309
- Pathways
- Mitotic G1-G1/S Phases
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