Recombinant PTBP1 antibody
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- Target See all PTBP1 Antibodies
- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PTBP1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PTBP1
- Clone
- 8A1
- Isotype
- IgG
- Top Product
- Discover our top product PTBP1 Primary Antibody
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anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibody
Verified PTBP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Goat Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-144) antibodyPTBP1 Reactivity: Human WB, ELISA, IF, IHC (p), IP Host: Mouse Monoclonal 3H8 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-100) antibodyPTBP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-290) antibodyPTBP1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 Reactivity: Human WB, IHC, IF Host: Rabbit Monoclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (N-Term) antibodyPTBP1 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 26-55), (N-Term) antibodyPTBP1 Reactivity: Human WB Host: Rabbit Polyclonal RB40967 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 1-557) antibodyPTBP1 Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) (AA 45-145) antibodyPTBP1 Reactivity: Human WB, IHC, ELISA, IF, IHC (p) Host: Mouse Monoclonal 3H8 unconjugated
anti-Polypyrimidine Tract Binding Protein 1 (PTBP1) antibodyPTBP1 Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PTBP1 (Polypyrimidine Tract Binding Protein 1 (PTBP1))
- Alternative Name
- PTBP1 (PTBP1 Products)
- Background
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Background: Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Aliases: Polypyrimidine tract-binding protein 1 (PTB) (57 kDa RNA-binding protein PPTB-1) (Heterogeneous nuclear ribonucleoprotein I) (hnRNP I), PTBP1, PTB
- UniProt
- P26599
- Pathways
- Regulation of Muscle Cell Differentiation
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