Recombinant PKM antibody
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- Target See all PKM Antibodies
- PKM (Pyruvate Kinase M1/2 (PKM))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PKM antibody is un-conjugated
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Application
- ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Cross-Reactivity
- Human, Mouse
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PKM2
- Clone
- 7B2
- Isotype
- IgG
- Top Product
- Discover our top product PKM Primary Antibody
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anti-Pyruvate Kinase M1/2 (PKM) (AA 2-531) antibody
PKM Reactivity: Human ELISA, WB, IHC, IF, IP, FACS Host: Mouse Monoclonal 6C3C7 unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 11-221) antibodyPKM Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 185-461) antibodyPKM Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (Internal Region) antibodyPKM Reactivity: Human, Mouse, Rat ELISA, WB, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 2-192) antibodyPKM Reactivity: Human ELISA, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM Reactivity: Human ELISA, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pSer37) antibodyPKM Reactivity: Human, Mouse, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) antibodyPKM Reactivity: Human, Mouse, Rat ELISA, WB, IHC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (pTyr105) antibodyPKM Reactivity: Human, Mouse ELISA, WB, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Pyruvate Kinase M1/2 (PKM) (AA 475-500), (N-Term) antibodyPKM Reactivity: Human WB, IHC (p) Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200, IP:1:200-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PKM (Pyruvate Kinase M1/2 (PKM))
- Alternative Name
- PKM (PKM Products)
- Background
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Background: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
Aliases: Pyruvate kinase PKM (EC 2.7.1.40) (Cytosolic thyroid hormone-binding protein) (CTHBP) (Opa-interacting protein 3) (OIP-3) (Pyruvate kinase 2/3) (Pyruvate kinase muscle isozyme) (Thyroid hormone-binding protein 1) (THBP1) (Tumor M2-PK) (p58), PKM, OIP3 PK2 PK3 PKM2
- UniProt
- P14618
- Pathways
- Warburg Effect
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