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Recombinant MLKL antibody (pSer358)

MLKL Reactivity: Human ELISA, IHC Host: Rabbit Monoclonal 4A6 unconjugated Recombinant Antibody
Catalog No. ABIN7127713
  • Target See all MLKL Antibodies
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Antibody Type
    Recombinant Antibody
    Binding Specificity
    • 11
    • 10
    • 10
    • 9
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer358
    Reactivity
    • 55
    • 40
    • 17
    • 1
    • 1
    Human
    Host
    • 67
    • 7
    Rabbit
    Clonality
    • 61
    • 13
    Monoclonal
    Conjugate
    • 32
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    This MLKL antibody is un-conjugated
    Application
    • 33
    • 28
    • 13
    • 11
    • 6
    • 5
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    Cross-Reactivity
    Human
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Phospho-MLKL (S358)
    Clone
    4A6
    Isotype
    IgG
    Top Product
    Discover our top product MLKL Primary Antibody
  • Application Notes
    Recommended dilution: IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Alternative Name
    MLKL (MLKL Products)
    Synonyms
    MLKL antibody, 9130019I15Rik antibody, mixed lineage kinase domain like pseudokinase antibody, mixed lineage kinase domain-like antibody, MLKL antibody, mlkl antibody, Mlkl antibody
    Background

    Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

    Aliases: Mixed lineage kinase domain-like protein, hMLKL, MLKL

    UniProt
    Q8NB16
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