Recombinant LAT antibody (pTyr191)
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- Target See all LAT Antibodies
- LAT (Linker For Activation of T Cells (LAT))
- Antibody Type
- Recombinant Antibody
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Binding Specificity
- pTyr191
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This LAT antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Phospho-LAT (Y191)
- Clone
- 2E4
- Isotype
- IgG
- Top Product
- Discover our top product LAT Primary Antibody
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anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibody
LAT Reactivity: Human WB, IP, FACS Host: Mouse Monoclonal LAT-01 unconjugated
anti-Linker For Activation of T Cells (LAT) antibodyLAT Reactivity: Human, Mouse, Rat WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 1-233) antibodyLAT Reactivity: Human WB, ELISA, IHC (p) Host: Mouse Monoclonal 3B11-1D5 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 30-237) antibodyLAT Reactivity: Mouse WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (pTyr161) antibodyLAT Reactivity: Human ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Cytoplasmic Domain) antibodyLAT Reactivity: Human WB, IHC, IP, IHC (p) Host: Mouse Monoclonal LAT1111 unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 25-221) antibodyLAT Reactivity: Human WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (AA 33-227) antibodyLAT Reactivity: Rat WB, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) antibodyLAT Reactivity: Human, Mouse, Rat WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Linker For Activation of T Cells (LAT) (Tyr255) antibodyLAT Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- LAT (Linker For Activation of T Cells (LAT))
- Alternative Name
- LAT (LAT Products)
- Synonyms
- LAT antibody, lat antibody, LAT1 antibody, pp36 antibody, linker for activation of T-cells antibody, linker for activation of T cells antibody, LAT antibody, lat antibody, Lat antibody
- Background
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Background: Required for TCR (T-cell antigen receptor)- and pre-TCR-mediated signaling, both in mature T-cells and during their development. Involved in FCGR3 (low affinity immunoglobulin gamma Fc region receptor III)-mediated signaling in natural killer cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores, PKC activation, MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1, GRB2, GRAP2, and other signaling molecules.
Aliases: Linker for activation of T-cells family member 1, 36 kDa phospho-tyrosine adapter protein, pp36, p36-38, LAT
- UniProt
- O43561
- Pathways
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway
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