Recombinant PABPN1 antibody
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- Target See all PABPN1 Antibodies
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PABPN1 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human PABPN1
- Clone
- 6C3
- Isotype
- IgG
- Top Product
- Discover our top product PABPN1 Primary Antibody
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anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibody
PABPN1 Reactivity: Human, Mouse, Rat IF, IHC Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 Reactivity: Human, Mouse, Dog, Rat, Rabbit, Cow, Guinea Pig WB, ICC Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) antibodyPABPN1 Reactivity: Human WB, IF, ICC, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (N-Term) antibodyPABPN1 Reactivity: Human, Dog, Rat, Rabbit, Cow, Guinea Pig, Pig, Monkey WB, IHC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (AA 1-100) antibodyPABPN1 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (C-Term) antibodyPABPN1 Reactivity: Human, Mouse WB, ELISA, IF, IHC, ICC Host: Rabbit Polyclonal unconjugated
anti-Poly A Binding Protein Nuclear 1 (PABPN1) (AA 270-298), (C-Term) antibodyPABPN1 Reactivity: Human WB Host: Rabbit Polyclonal RB36573 unconjugated
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- Application Notes
- Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200, FC:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))
- Alternative Name
- PABPN1 (PABPN1 Products)
- Background
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Background: Involved in the 3'-end formation of mRNA precursors (pre-mRNA) by the addition of a poly(A) tail of 200-250 nt to the upstream cleavage product (By similarity). Stimulates poly(A) polymerase (PAPOLA) conferring processivity on the poly(A) tail elongation reaction and controls also the poly(A) tail length (By similarity). Increases the affinity of poly(A) polymerase for RNA (By similarity). Is also present at various stages of mRNA metabolism including nucleocytoplasmic trafficking and nonsense-mediated decay (NMD) of mRNA. Cooperates with SKIP to synergistically activate E-box-mediated transcription through MYOD1 and may regulate the expression of muscle-specific genes (PubMed:11371506). Binds to poly(A) and to poly(G) with high affinity (By similarity). May protect the poly(A) tail from degradation (By similarity).
Aliases: Polyadenylate-binding protein 2 (PABP-2) (Poly(A)-binding protein 2) (Nuclear poly(A)-binding protein 1) (Poly(A)-binding protein II) (PABII) (Polyadenylate-binding nuclear protein 1), PABPN1, PAB2 PABP2
- UniProt
- Q86U42
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