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Recombinant Menin antibody

MEN1 Reactivity: Human WB, ELISA Host: Rabbit Monoclonal 8G11 unconjugated Recombinant Antibody
Catalog No. ABIN7127614
  • Target See all Menin (MEN1) Antibodies
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 80
    • 37
    • 30
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 73
    • 5
    • 2
    • 1
    Rabbit
    Clonality
    • 77
    • 4
    Monoclonal
    Conjugate
    • 36
    • 7
    • 7
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Menin antibody is un-conjugated
    Application
    • 53
    • 38
    • 23
    • 17
    • 13
    • 13
    • 9
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Cross-Reactivity
    Human
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Menin
    Clone
    8G11
    Isotype
    IgG
    Top Product
    Discover our top product MEN1 Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    Menin (MEN1) (Multiple Endocrine Neoplasia 1 (MEN1))
    Alternative Name
    MEN1 (MEN1 Products)
    Synonyms
    MEAI antibody, SCG2 antibody, menin antibody, meai antibody, scg2 antibody, AW045611 antibody, menin 1 antibody, menin 1 L homeolog antibody, multiple endocrine neoplasia I antibody, multiple endocrine neoplasia 1 antibody, MEN1 antibody, men1 antibody, men1.L antibody, Men1 antibody
    Background

    Background: Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.

    Aliases: Menin, MEN1, SCG2

    UniProt
    O00255
    Pathways
    Chromatin Binding, Positive Regulation of Endopeptidase Activity
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