Recombinant Lamin A/C antibody
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- Target See all Lamin A/C (LMNA) Antibodies
- Lamin A/C (LMNA)
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This Lamin A/C antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP), Flow Cytometry (FACS)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human LMNA
- Clone
- 4H7
- Isotype
- IgG
- Top Product
- Discover our top product LMNA Primary Antibody
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anti-Lamin A/C (LMNA) (AA 403-572) antibody
LMNA Reactivity: Human WB, IHC, IF, IP Host: Rabbit Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyKO Validated LMNA Reactivity: Human WB, IF, IP, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Lamin A/C (LMNA) (pSer392) antibodyLMNA Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyKO Validated LMNA Reactivity: Human WB, IHC, IF, IP Host: Rabbit Monoclonal unconjugated
anti-Lamin A/C (LMNA) antibodyLMNA Reactivity: Human WB, IHC, ELISA Host: Mouse Monoclonal 4E7 unconjugated
anti-Lamin A/C (LMNA) (AA 481-646) antibodyLMNA Reactivity: Human, Mouse, Rat WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Lamin A/C (LMNA) (AA 455-469) antibodyLMNA Reactivity: Human, Mouse, Rat WB, ICC, IHC (p) Host: Rabbit Polyclonal unconjugated
anti-Lamin A/C (LMNA) antibodyLMNA Reactivity: Human, Mouse, Rat, Cow, Dog WB, IHC, ICC, FACS, IHC (fro) Host: Mouse Monoclonal 133A2 unconjugated
anti-Lamin A/C (LMNA) (C-Term) antibodyLMNA Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Monkey, Horse, Rabbit, Hamster, Chicken, Sheep, Guinea Pig, Avian, Cat, Donkey, Goat WB Host: Goat Polyclonal unconjugated
anti-Lamin A/C (LMNA) (AA 1-664) antibodyLMNA Reactivity: Human WB, IF Host: Mouse Polyclonal unconjugated
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- Application Notes
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200, IP:1:200-1:1000,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- Lamin A/C (LMNA)
- Alternative Name
- LMNA (LMNA Products)
- Background
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Background: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920).
Aliases: Prelamin-A/C, Lamin-A/C, 70 kDa lamin, Renal carcinoma antigen NY-REN-32, LMNA, LMN1
- UniProt
- P02545
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus
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