Recombinant GZMB antibody
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- Target See all GZMB Antibodies
- GZMB (Granzyme B (GZMB))
- Antibody Type
- Recombinant Antibody
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This GZMB antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
- Cross-Reactivity
- Human
- Purification
- Affinity-chromatography
- Immunogen
- A synthesized peptide derived from human Granzyme B
- Clone
- 6A1
- Isotype
- IgG
- Top Product
- Discover our top product GZMB Primary Antibody
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anti-Granzyme B (GZMB) (AA 21-247) antibody
GZMB Reactivity: Human WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human WB, IHC, StM Host: Mouse Monoclonal GZMB-3014 unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Non-Human Primate FACS Host: Mouse Monoclonal CLB-GB11 unconjugated
anti-Granzyme B (GZMB) (AA 21-130) antibodyGZMB Reactivity: Human, Mouse WB, ELISA, FACS, IHC (p), IF (p), IHC (fro), IF (cc) Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) antibodyGZMB Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IF, ICC Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 175-203), (C-Term) antibodyGZMB Reactivity: Human WB, FACS, IHC (p) Host: Rabbit Polyclonal RB19353 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human IHC, ELISA Host: Mouse Monoclonal 2G12G7 unconjugated
anti-Granzyme B (GZMB) (AA 1-247) antibodyGZMB Reactivity: Human WB, IP Host: Rabbit Polyclonal unconjugated
anti-Granzyme B (GZMB) (AA 73-187) antibodyGZMB Reactivity: Human IHC, StM Host: Mouse Monoclonal GZMB-3056 unconjugated
anti-Granzyme B (GZMB) (AA 21-247) antibodyGZMB Reactivity: Human WB, IHC, IF, IHC (p) Host: Mouse Monoclonal 4E4 unconjugated
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- Application Notes
- Recommended dilution: IHC:1:50-1:200, IF:1:20-1:200,
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- GZMB (GZMB Products)
- Background
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Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Aliases: Granzyme B (EC 3.4.21.79) (C11) (CTLA-1) (Cathepsin G-like 1) (CTSGL1) (Cytotoxic T-lymphocyte proteinase 2) (Lymphocyte protease) (Fragmentin-2) (Granzyme-2) (Human lymphocyte protein) (HLP) (SECT) (T-cell serine protease 1-3E), GZMB, CGL1 CSPB CTLA1 GRB
- UniProt
- P10144
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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