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Recombinant c-FOS antibody

c-Fos Reactivity: Human WB, ELISA, IHC, FACS, IF Host: Rabbit Monoclonal 14C10 unconjugated Recombinant Antibody
Catalog No. ABIN7127496
  • Target See all c-FOS (c-Fos) Antibodies
    c-FOS (c-Fos) (c-Fos)
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 213
    • 162
    • 143
    • 13
    • 13
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Human
    Host
    • 201
    • 39
    • 6
    • 1
    Rabbit
    Clonality
    • 205
    • 41
    Monoclonal
    Conjugate
    • 107
    • 13
    • 11
    • 9
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    This c-FOS antibody is un-conjugated
    Application
    • 202
    • 80
    • 80
    • 76
    • 39
    • 35
    • 34
    • 25
    • 14
    • 13
    • 10
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)
    Cross-Reactivity
    Human, Mouse
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human FOS
    Clone
    14C10
    Isotype
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200, IF:1:20-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    c-FOS (c-Fos) (c-Fos)
    Alternative Name
    FOS (c-Fos Products)
    Synonyms
    AP-1 antibody, C-FOS antibody, p55 antibody, c-fos antibody, D12Rfj1 antibody, cFos antibody, cFOS antibody, fos antibody, Fos proto-oncogene, AP-1 transcription factor subunit antibody, FBJ osteosarcoma oncogene antibody, proto-oncogene c-Fos-like antibody, FOS antibody, Fos antibody, LOC101078177 antibody
    Background

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    Aliases: Proto-oncogene c-Fos, Cellular oncogene fos, G0/G1 switch regulatory protein 7, FOS, G0S7

    UniProt
    P01100
    Pathways
    S100 Proteins
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