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Recombinant FAS antibody

FAS Reactivity: Human WB, IHC, ELISA Host: Rabbit Monoclonal 2B6 unconjugated Recombinant Antibody
Catalog No. ABIN7321618
  • Target See all FAS Antibodies
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Antibody Type
    Recombinant Antibody
    Reactivity
    • 209
    • 62
    • 59
    • 19
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 156
    • 87
    • 4
    • 2
    • 1
    • 1
    • 1
    Rabbit
    Clonality
    • 156
    • 94
    • 1
    Monoclonal
    Conjugate
    • 112
    • 26
    • 25
    • 13
    • 11
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FAS antibody is un-conjugated
    Application
    • 156
    • 113
    • 71
    • 56
    • 34
    • 34
    • 26
    • 26
    • 26
    • 19
    • 16
    • 9
    • 8
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Cross-Reactivity
    Human
    Purification
    Affinity-chromatography
    Immunogen
    A synthesized peptide derived from human Fas
    Clone
    2B6
    Isotype
    IgG
    Top Product
    Discover our top product FAS Primary Antibody
  • Application Notes
    Recommended dilution: WB:1:500-1:5000, IHC:1:50-1:200,
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target
    FAS (TNF Receptor Superfamily, Member 6 (FAS))
    Alternative Name
    FAS (FAS Products)
    Synonyms
    ALPS1A antibody, APO-1 antibody, APT1 antibody, CD95 antibody, FAS1 antibody, FASTM antibody, TNFRSF6 antibody, AI196731 antibody, APO1 antibody, TNFR6 antibody, Tnfrsf6 antibody, lpr antibody, Fas cell surface death receptor antibody, Fas (TNF receptor superfamily member 6) antibody, FAS antibody, Fas antibody, fas antibody
    Background

    Background: Receptor for TNFSF6/FASLG. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. The secreted isoforms 2 to 6 block apoptosis (in vitro).

    Aliases: Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95), FAS, APT1 FAS1 TNFRSF6

    UniProt
    P25445
    Pathways
    p53 Signaling, Apoptosis, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
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