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ZMYM3 antibody

ZMYM3 Reactivity: Human WB, IF, IHC (f), FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7127138
  • Target See all ZMYM3 Antibodies
    ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
    Reactivity
    • 21
    • 10
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    Human
    Host
    • 20
    • 1
    Mouse
    Clonality
    • 20
    • 1
    Monoclonal
    Conjugate
    • 17
    • 2
    • 1
    • 1
    This ZMYM3 antibody is un-conjugated
    Application
    • 13
    • 8
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)), Flow Cytometry (FACS)
    Specificity
    Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZMYM3 (zinc finger MYM-type protein 3), also known as ZNF261 (zinc finger protein 261), XFIM, DXS6673E or MYM, is a 1,370 amino acid nuclear protein that contains nine MYM-type zinc fingers. Expressed in a variety of tissues, including heart, muscle and brain, ZMYM3 is thought to function as part of a histone deacetylase-containing complex that contains other proteins, such as HDAC1 and HDAC2, and may play a role in gene silencing through the modification of chromatin structure. Defects in the gene encoding ZMYM3 that lead to chromosomal translocations may be a cause of X-linked mental retardation. Two isoforms of ZMYM3 exist due to alternative splicing events.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human ZMYM3 protein
    Isotype
    IgG2a
    Top Product
    Discover our top product ZMYM3 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL),Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa or Raji cells. Ubiquitious nuclear expression.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    ZMYM3 (Zinc Finger Protein 261 (ZMYM3))
    Alternative Name
    ZMYM3 (ZMYM3 Products)
    Synonyms
    ZNF261 antibody, si:ch211-173p18.2 antibody, DXS6673E antibody, MYM antibody, XFIM antibody, ZNF198L2 antibody, 9030216B10Rik antibody, AW122925 antibody, DXS6673El antibody, Zfp261 antibody, zinc finger MYM-type containing 3 antibody, si:ch211-173p18.3 antibody, zinc finger, MYM-type 3 antibody, ZMYM3 antibody, si:ch211-173p18.3 antibody, Zmym3 antibody
    Background
    DXS6673E, KIAA0385, MYM, XFIM, ZFP261, Zinc finger MYM type 3, Zinc finger MYM type protein 3, Zinc finger MYM-type protein 3, Zinc finger protein 261, ZNF198L2, ZNF261,ZMYM3
    Cellular localisation: Nucleus.
    Molecular Weight
    152kDa
    Gene ID
    9203, 522684
    UniProt
    Q14202
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