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INSM2 antibody (AA 432-540)

INSM2 Reactivity: Human IHC (f) Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7127097
  • Target See all INSM2 Antibodies
    INSM2 (Insulinoma-Associated 2 (INSM2))
    Binding Specificity
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 432-540
    Reactivity
    • 17
    • 13
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 17
    Mouse
    Clonality
    • 17
    Monoclonal
    Conjugate
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This INSM2 antibody is un-conjugated
    Application
    • 10
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription. INSM2 may function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant fragment of human INSM2 protein (around aa 432-540) (exact sequence is proprietary)
    Isotype
    IgG1
    Top Product
    Discover our top product INSM2 Primary Antibody
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes),Optimal dilution for a specific application should be determined.

    Positive_Control: Human pancreas tissue.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    INSM2 (Insulinoma-Associated 2 (INSM2))
    Alternative Name
    INSM2 (INSM2 Products)
    Synonyms
    INSM2 antibody, IA-6 antibody, IA6 antibody, mlt1 antibody, Mlt1 antibody, INSM transcriptional repressor 2 antibody, insulinoma-associated 2 antibody, INSM2 antibody, Insm2 antibody
    Background
    IA1, Insulinoma associated protein 2 (IA2), Zinc finger protein IA6,Insulinoma Associated 2 / INSM2
    Cellular localisation: Nuclear
    Molecular Weight
    58kDa
    Gene ID
    84684, 62813
    UniProt
    Q96T92
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