TRIM27 antibody
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- Target See all TRIM27 Antibodies
- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This TRIM27 antibody is un-conjugated
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Application
- Immunofluorescence (IF), Flow Cytometry (FACS)
- Specificity
- Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.
- Cross-Reactivity (Details)
- Human. Predicted to react with Mouse and Rat.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human TRIM27 protein
- Isotype
- IgG2a
- Top Product
- Discover our top product TRIM27 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.
Positive_Control: HeLa, U87 or Raji cells.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- TRIM27 (Tripartite Motif Containing 27 (TRIM27))
- Alternative Name
- TRIM27 (TRIM27 Products)
- Synonyms
- RFP antibody, RNF76 antibody, AW538890 antibody, Gm19403 antibody, Rfp antibody, TRIM27 antibody, Rfp1 antibody, tripartite motif containing 27 antibody, tripartite motif-containing 27 antibody, TRIM27 antibody, Trim27 antibody
- Background
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AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP,TRIM27
Cellular localisation: Nucleus. Cytoplasm. Nucleus > PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies. - Molecular Weight
- 58.49kDa
- Gene ID
- 5987, 440382
- UniProt
- P14373
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