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TRIM27 antibody

TRIM27 Reactivity: Human IF, FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7126897
  • Target See all TRIM27 Antibodies
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Reactivity
    • 40
    • 21
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Human
    Host
    • 39
    • 1
    Mouse
    Clonality
    • 39
    • 1
    Monoclonal
    Conjugate
    • 16
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TRIM27 antibody is un-conjugated
    Application
    • 25
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    Defects in TRIM27 are a cause of thyroid papillary carcinoma (TPC) [MIM:188550]. TPC is a common tumor of the thyroid that typically arises as an irregular, solid or cystic mass from otherwise normal thyroid tissue. Papillary carcinomas are malignant neoplasm characterized by the formation of numerous, irregular, finger-like projections of fibrous stroma that is covered with a surface layer of neoplastic epithelial cells. Note=A chromosomal aberration involving TRIM27/RFP is found in thyroid papillary carcinomas. Translocation t(6,10)(p21.3,q11.2) with RET. The translocation generates TRIM27/RET and delta TRIM27/RET oncogenes.
    Cross-Reactivity (Details)
    Human. Predicted to react with Mouse and Rat.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human TRIM27 protein
    Isotype
    IgG2a
    Top Product
    Discover our top product TRIM27 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL),Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, U87 or Raji cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    TRIM27 (Tripartite Motif Containing 27 (TRIM27))
    Alternative Name
    TRIM27 (TRIM27 Products)
    Synonyms
    RFP antibody, RNF76 antibody, AW538890 antibody, Gm19403 antibody, Rfp antibody, TRIM27 antibody, Rfp1 antibody, tripartite motif containing 27 antibody, tripartite motif-containing 27 antibody, TRIM27 antibody, Trim27 antibody
    Background
    AW538890, DAAP-182E11.3, MGC189472, Ret finger protein, RFP transforming protein, Rfp1, RING finger protein 76, RNF76, Tripartite motif-containing protein 27, Zinc finger protein RFP,TRIM27
    Cellular localisation: Nucleus. Cytoplasm. Nucleus > PML body. Nuclear or cytoplasmic depending on the cell type (By similarity). Colocalized with PML and EIF3S6 in nuclear bodies.
    Molecular Weight
    58.49kDa
    Gene ID
    5987, 440382
    UniProt
    P14373
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