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E4F1 antibody

E4F1 Reactivity: Human IF, FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7126308
  • Target See all E4F1 Antibodies
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Reactivity
    • 10
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 7
    • 3
    Mouse
    Clonality
    • 9
    • 1
    Monoclonal
    Conjugate
    • 10
    This E4F1 antibody is un-conjugated
    Application
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    E4F1 (E4F transcription factor 1), also known as E4F, is a 784 amino acid protein that localizes to both the nucleus and the cytoplasm and contains 9 C2H2-type zinc fingers. Expressed ubiquitously in adult and fetal tissues, E4F1 exists as a homodimer that binds DNA and is thought to act as a transcriptional repressor and may also play a role in cell survival and growth via cell cycle control. Additionally, E4F1 is thought to function as a ubiquitin ligase that mediates the ubiquitination (and subsequent degradation) of target proteins and may be involved in the p53 tumor suppressor pathway. E4F1, which may be post-translationally phosphorylated or sumoylated, is subject to proteolytic cleavage which results in the creation of a short peptide with specific DNA binding capabilities.
    Cross-Reactivity (Details)
    Human
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human E4F1 protein
    Isotype
    IgG1
    Top Product
    Discover our top product E4F1 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa, Jurkat or MCF7 cells.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    E4F1 (E4F Transcription Factor 1 (E4F1))
    Alternative Name
    E4F1 (E4F1 Products)
    Synonyms
    e4f antibody, MGC147041 antibody, E4F antibody, Dnase1l2 antibody, zgc:114190 antibody, E4F transcription factor 1 antibody, E4F transcription factor 1 S homeolog antibody, E4F1 antibody, e4f1 antibody, e4f1.S antibody, E4f1 antibody
    Background
    E4F transcription factor 1, isoform CRA_b, P120E4F transcription factor, p50E4F, Putative E3 ubiquitin-protein ligase E4F1, RING type E3 ubiquitin transferase E4F1, Transcription factor E4F1,E4F1
    Cellular localisation: Nucleus.
    Molecular Weight
    83kDa
    Gene ID
    1877, 513268
    UniProt
    Q66K89
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