Recombinant CGA antibody (AA 1-100)

Catalog No. ABIN7504153

Product Details anti-CGA Antibody

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Antibody Type: Recombinant Antibody

Binding Specificity: AA 1-100

Reactivity: Synthetic

Host: Rabbit

Clonality: Monoclonal

Conjugate: This CGA antibody is un-conjugated

Application: Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

Specificity: Human chorionic gonadotropin antibody (hCG) is a glycoprotein hormone synthesized in syncytiotrophoblastic cells of placenta and in certain trophoblastic tumors. The hormone-specific alpha chains have molecular weights of 13 kDa. HCG is found in moles and choriocarcinoma, chorionic components of germ cell tumors, and syncytiotrophoblast like cells in seminoma/dysgerminoma and embryonal carcinoma. In diagnostic pathology, hCG is a useful marker for classification of germ cell tumors, identification of extragonadal germ cell tumors.

Cross-Reactivity (Details): Human.

Purification: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Synthetic peptide corresponding to residues within aa1-100 of hCG was used as an immunogen

Isotype: IgG

Application Details

Application Notes:

Positive Control: Human placenta.

Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95 °C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.

Restrictions: For Research Use only

Handling

Concentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.

Expiry Date: 24 months

Target Details for CGA

Target: CGA (Glycoprotein Hormones, alpha Polypeptide (CGA))

Alternative Name: CGA (CGA Products)

Synonyms: CG-ALPHA antibody, FSHA antibody, GPHA1 antibody, GPHa antibody, HCG antibody, LHA antibody, TSHA antibody, CG-alpha antibody, GPHalpha antibody, Tsha antibody, aGSU antibody, alpha-GSU antibody, alphaGSU antibody, alphaSU antibody, CGA antibody, FSH-alpha antibody, LSH-alpha antibody, TSH-alpha antibody, cg-alpha antibody, cga antibody, cga-a antibody, cga-b antibody, fsha antibody, gpha antibody, gpha1 antibody, hcg antibody, lha antibody, tsha antibody, GTH-alpha antibody, gsu-alpha antibody, glycoprotein hormones, alpha polypeptide antibody, glycoprotein hormones, alpha subunit antibody, chromogranin A antibody, glycoprotein hormones, alpha polypeptide L homeolog antibody, CGA antibody, Cga antibody, CHGA antibody, cga.L antibody, cga antibody

Background: CG-alpha, CGA, Chorionic Gonadotrophin Alpha, Follicle Stimulating Hormone Alpha, Follitropin Alpha, FSH-alpha, FSHA, GPH Alpha, GPHA1, LHA, LH-alpha, Luteinizing Hormone Alpha, Lutropin Alpha, Thyroid Stimulating Hormone Alpha, Thyrotropin Alpha, TSHA,HCG-beta (Pregnancy & Choriocarcinoma Marker)
Cellular localisation: Cytoplasmic, secreted

Molecular Weight: 13kDa

Gene ID: 1081, 119689

UniProt: P01215

Pathways: Metabolism of Steroid Hormones and Vitamin D, Thyroid Hormone Synthesis, Hormone Transport, Peptide Hormone Metabolism