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IRF9 antibody

IRF9 Reactivity: Human IF, FACS Host: Mouse Monoclonal unconjugated
Catalog No. ABIN7504160
  • Target See all IRF9 Antibodies
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Reactivity
    • 46
    • 16
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Host
    • 42
    • 5
    • 1
    Mouse
    Clonality
    • 44
    • 3
    Monoclonal
    Conjugate
    • 23
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IRF9 antibody is un-conjugated
    Application
    • 36
    • 15
    • 13
    • 13
    • 9
    • 9
    • 7
    • 3
    • 2
    • 2
    • 1
    Immunofluorescence (IF), Flow Cytometry (FACS)
    Specificity
    Transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with IRF9/ISGF3G to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
    Cross-Reactivity (Details)
    Human
    Purification
    200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
    Immunogen
    Recombinant full-length human IRF9 protein
    Isotype
    IgG2a
    Top Product
    Discover our top product IRF9 Primary Antibody
  • Application Notes

    Positive Control: MCF-7, Jurkat or K562 cells.

    Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

    Restrictions
    For Research Use only
  • Concentration
    200 μg/mL
    Buffer
    Prepared in 10 mM PBS with 0.05 % BSA and 0.05 % azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-80 °C
    Storage Comment
    Antibody with azide - store at 2 to 8 °C. Antibody is stable for 24 months. Non-hazardous. Also available WITHOUT BSA & azide at 1.0mg/ml.
    Expiry Date
    24 months
  • Target
    IRF9 (Interferon Regulatory Factor 9 (IRF9))
    Alternative Name
    IRF9 (IRF9 Products)
    Synonyms
    IRF-9 antibody, ISGF3 antibody, ISGF3G antibody, p48 antibody, zgc:92097 antibody, Irf-9 antibody, Isgf3g antibody, interferon regulatory factor 9 antibody, IRF9 antibody, irf9 antibody, Irf9 antibody
    Background
    IFN alpha responsive transcription factor subunit, Interferon regulatory factor 9, Interferon-stimulated gene factor 3 gamma, interferon-stimulated transcription factor 3, gamma 48 kDa, IRF-9, ISGF-3 gamma, ISGF3 p48 subunit, ISGF3G, p48, Transcriptional regulator ISGF3 subunit gamma,Interferon regulatory factor 9 / IRF-9
    Cellular localisation: Cytoplasm. Nucleus. Translocated into the nucleus upon activation by IFN-alpha/beta.
    Molecular Weight
    43.34kDa
    Gene ID
    10379, 1706
    UniProt
    Q00978
    Pathways
    JAK-STAT Signaling, Interferon-gamma Pathway, Hepatitis C
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