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ZCCHC6 antibody

ZCCHC6 Reactivity: Human, Mouse, Rat WB, IP, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7121053
  • Target See all ZCCHC6 Antibodies
    ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
    Reactivity
    Human, Mouse, Rat
    Host
    • 3
    • 2
    Rabbit
    Clonality
    • 5
    Polyclonal
    Conjugate
    • 5
    This ZCCHC6 antibody is un-conjugated
    Application
    Western Blotting (WB), Immunoprecipitation (IP), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    zinc finger, CCHC domain containing 6
    Isotype
    IgG
    Top Product
    Discover our top product ZCCHC6 Primary Antibody
  • Application Notes
    WB: 1:500-1:5000, IP: 1:500-1:5000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    ZCCHC6 (Zinc Finger, CCHC Domain Containing 6 (ZCCHC6))
    Alternative Name
    ZCCHC6 (ZCCHC6 Products)
    Synonyms
    PAPD6 antibody, 6030448M23Rik antibody, AA420405 antibody, zinc finger CCHC-type containing 6 antibody, zinc finger, CCHC domain containing 6 antibody, ZCCHC6 antibody, Zcchc6 antibody
    Background
    Synonyms:DKFZp666B142, DKFZp686C11112, DKFZp686F119, DKFZp686I1269, HS2, KIAA1711, PAPD6, Terminal uridylyltransferase 7, TUT7, TUTase 7, ZCCHC6 Background:Uridylyltransferase that mediates the terminal uridylation of mRNAs with short(less than 25 nucleotides) poly(A) tails, hence facilitating global mRNA decay(PubMed:19703396, PubMed:25480299). Involved in microRNA(miRNA)-induced gene silencing through uridylation of deadenylated miRNA targets(PubMed:25480299). Also acts as a suppressor of miRNA biogenesis by mediating the terminal uridylation of some miRNA precursors, including that of let-7(pre-let-7). Uridylated pre-let-7 RNA is not processed by Dicer and undergo degradation. Pre-let-7 uridylation is strongly enhanced in the presence of LIN28A(PubMed:22898984). Due to functional redundancy between ZCCHC6 and ZCCHC11, the identification of the specific role of each of these proteins is difficult.
    Molecular Weight
    171 kDa
    Gene ID
    79670
    UniProt
    Q5VYS8
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