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ZFP36L2 antibody
ZFP36L2
Reactivity: Human, Mouse, Rat
WB, ELISA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZFP36L2 Antibody
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Target
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ZFP36L2
(Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))
Reactivity
All reactivities for ZFP36L2 antibodies
Human, Mouse, Rat
Host
All hosts for ZFP36L2 antibodies
Rabbit
Clonality
All clonalities for ZFP36L2 antibodies
Polyclonal
Conjugate
All conjugates for ZFP36L2 antibodies
This ZFP36L2 antibody is un-conjugated
Application
All applications for ZFP36L2 antibodies
Western Blotting (WB), ELISA
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
zinc finger protein 36, C3H type-like 2
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:200-1:2000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for ZFP36L2
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Target
ZFP36L2
(Zinc Finger Protein 36, C3H Type-Like 2 (ZFP36L2))
Alternative Name
ZFP36L2 (ZFP36L2 Products )
Synonyms
BRF2 antibody, ERF-2 antibody, ERF2 antibody, RNF162C antibody, TIS11D antibody, Brf2 antibody, Tis11d antibody, fi22c11 antibody, wu:fi22c11 antibody, zgc:76924 antibody, ZFP36L2 antibody, XC3H-3 antibody, XC3H-3b antibody, c3h-3 antibody, zfp36l2 antibody, brf2 antibody, erf-2 antibody, erf2 antibody, rnf162c antibody, tis11d antibody, cb198 antibody, cb480 antibody, fk89d11 antibody, id:ibd1247 antibody, sb:cb198 antibody, sb:cb480 antibody, wu:fb80h11 antibody, wu:fb92f07 antibody, wu:fk89d11 antibody, zfp36l1 antibody, zgc:153979 antibody, XC3H-2 antibody, berg36 antibody, brf1 antibody, c3h-2 antibody, cmg1 antibody, erf-1 antibody, erf1 antibody, rnf162b antibody, tis11b antibody, zfp36l1-a antibody, zfp36l1-b antibody, ZFP36 ring finger protein like 2 antibody, zinc finger protein 36, C3H type-like 2 antibody, ZFP36 ring finger protein-like 2 S homeolog antibody, ZFP36 ring finger protein-like 2 L homeolog antibody, ZFP36 ring finger protein-like 2 antibody, zinc finger protein 36, C3H type-like 1a antibody, ZFP36 ring finger protein-like 1 L homeolog antibody, ZFP36L2 antibody, Zfp36l2 antibody, zfp36l2 antibody, zfp36l2.S antibody, zfp36l2.L antibody, zfp36l1a antibody, zfp36l1.L antibody
Background
Synonyms:BRF2, Butyrate response factor 2, EGF response factor 2, ERF 2, ERF2, Protein TIS11D, RNF162C, TIS11D, ZFP36L2 Background:mRNA-binding protein that plays a key role in self-renewal of erythroid cells in response to glucocorticoids. Specifically binds to the AU-rich element(ARE) in the 3'-UTR of target mRNAs, promoting their deadenylation and degradation(PubMed:14981510). Specifically expressed in burst-forming unit-erythroid(BFU-E) progenitors in response to glucocorticoids and acts as a negative regulator of erythroid cell differentiation: promotes self-renewal of erythroid cells by binding mRNAs that are induced or highly expressed during terminal erythroid differentiation and promotes their degradation, preventing erythroid cell differentiation. Down-regulated during erythroid differentiation from the BFU-E stage, stabilizing mRNAs required for terminal differentiation(By similarity).
Molecular Weight
51 kDa
Gene ID
678
UniProt
P47974
Pathways
Stem Cell Maintenance
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