ZBTB7B antibody

Catalog No. ABIN7120925

Product Details anti-ZBTB7B Antibody

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB7B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: zinc finger and BTB domain containing 7B

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IF: 1:10-1:100, IP: 1:200-1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for ZBTB7B

Target: ZBTB7B (Zinc Finger and BTB Domain Containing 7B (ZBTB7B))

Alternative Name: ZBTB7B (ZBTB7B Products)

Synonyms: THPOK antibody, ZBTB15 antibody, ZFP-67 antibody, ZFP67 antibody, ZNF857B antibody, c-KROX antibody, hcKROX antibody, Thpok antibody, Zfp67 antibody, c-Krox antibody, ZBTB7B antibody, zbtb7b antibody, MGC130914 antibody, zinc finger and BTB domain containing 7B antibody, kruppel-related zinc finger protein hcKrox antibody, ZBTB7B antibody, Zbtb7b antibody, zbtb7b antibody

Background: Synonyms:C Krox, DKFZp686G01254, hcKrox, THPOK, ZBTB15, ZBTB7B, Zfp 67, ZFP67, Zinc finger protein 67 homolog, Zinc finger protein Th POK, ZNF857B Background:Transcription regulator that acts as a key regulator of lineage commitment of immature T-cell precursors. Necessary and sufficient for commitment of CD4 lineage, while its absence causes CD8 commitment. Development of immature T-cell precursors(thymocytes) to either the CD4 helper or CD8 killer T-cell lineages correlates precisely with their T-cell receptor specificity for major histocompatibility complex class II or class I molecules, respectively. Transcriptional repressor of the collagen COL1A1 and COL1A2 genes. May also function as a repressor of fibronectin and possibly other extracellular matrix genes(By similarity).

Molecular Weight: 58 kDa

Gene ID: 51043

UniProt: O15156