XPA antibody

Catalog No. ABIN7120881

This anti-XPA antibody is a Rabbit Polyclonal antibody detecting XPA in WB and ELISA. Suitable for Human, Mouse and Rat.

Quick Overview for XPA antibody (ABIN7120881)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPA antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-XPA Antibody

Purpose: XPA antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: xeroderma pigmentosum, complementation group A

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IF: 1:50-1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Alternative Name: XPA

Background:

Synonyms: DNA repair protein complementing XP-A cells|Xeroderma pigmentosum group A-complementing protein|XPA|XPAC

Background: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.

Molecular Weight: 42 kDa

Gene ID: 7507

UniProt: P23025

Pathways: DNA Damage Repair