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WRAP53 antibody

WRAP53 Reactivity: Human, Mouse, Rat WB, IHC, ELISA, IP Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7120809
  • Target See all WRAP53 Antibodies
    WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
    Reactivity
    Human, Mouse, Rat
    Host
    • 28
    • 6
    Rabbit
    Clonality
    • 31
    • 3
    Polyclonal
    Conjugate
    • 13
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This WRAP53 antibody is un-conjugated
    Application
    • 25
    • 13
    • 13
    • 6
    • 4
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    WD repeat containing, antisense to TP53
    Isotype
    IgG
    Top Product
    Discover our top product WRAP53 Primary Antibody
  • Application Notes
    WB: 1:500-1:5000, IHC: 1:20-1:200, IP: 1:200-1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    WRAP53 (WD Repeat Containing, Antisense To TP53 (WRAP53))
    Alternative Name
    WRAP53 (WRAP53 Products)
    Synonyms
    DKCB3 antibody, TCAB1 antibody, WDR79 antibody, Wdr79 antibody, BC021790 antibody, WD repeat containing antisense to TP53 antibody, WD repeat containing, antisense to TP53 antibody, WD repeat containing, antisense to Trp53 antibody, WRAP53 antibody, Wrap53 antibody
    Background
    Synonyms:FLJ10385, TCAB1, WDR79, WRAP53 Background:Essential component of the telomerase holoenzyme complex, a ribonucleoprotein complex essential for the replication of chromosome termini that elongates telomeres in most eukaryotes. In the telomerase holoenzyme complex, it controls telomerase localization to Cajal body. Required for delivery of TERC to telomeres during S phase and for telomerase activity. Binds small Cajal body RNAs(scaRNAs). The mRNA encoding this protein plays a critical role in the regulation of p53 expression at the post-transcriptional level, it is involved both in maintaining basal p53 mRNA levels and in p53 induction upon DNA damage.
    Molecular Weight
    72 kDa
    Gene ID
    55135
    UniProt
    Q9BUR4
    Pathways
    Telomere Maintenance
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