VPS54 antibody

Catalog No. ABIN7120717

Product Details anti-VPS54 Antibody

Target: VPS54 (Vacuolar Protein Sorting 54 Homolog (VPS54))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS54 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 54 homolog(S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000,IP: 1:200-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VPS54

Target: VPS54 (Vacuolar Protein Sorting 54 Homolog (VPS54))

Alternative Name: VPS54 (VPS54 Products)

Synonyms: 5330404P15Rik antibody, Hcc8 antibody, Vps54l antibody, mSLP8 antibody, wr antibody, HCC8 antibody, SLP-8p antibody, VPS54L antibody, WR antibody, hVps54L antibody, Vsp54 antibody, Vacuolar protein sorting-associated protein 54 antibody, VPS54 GARP complex subunit antibody, VPS54, GARP complex subunit antibody, vps-54 antibody, Vps54 antibody, VPS54 antibody

Background: Synonyms:HCC8, hVps54L, SLP 8p, Tumor antigen HOM HCC 8, Tumor antigen SLP 8p, VPS54, VPS54L Background:Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:18367545). Within the GARP complex, required to tether the complex to the TGN. Not involved in endocytic recycling(PubMed:25799061).

Molecular Weight: 111 kDa

Gene ID: 51542

UniProt: Q9P1Q0