VPS52 antibody

Catalog No. ABIN7120715

Product Details anti-VPS52 Antibody

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VPS52 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: vacuolar protein sorting 52 homolog(S. cerevisiae)

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000,IP: 1:500-1:5000,IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VPS52

Target: VPS52 (Vacuolar Protein Sorting 52 Homolog (VPS52))

Alternative Name: VPS52 (VPS52 Products)

Synonyms: ARE1 antibody, RP5-1033B10 antibody, SAC2 antibody, SACM2L antibody, dJ1033B10.5 antibody, Are1 antibody, Sacm2l antibody, D130068D18 antibody, D430041K17Rik antibody, fb94c11 antibody, sacm2l antibody, wu:fb94c11 antibody, VPS52, GARP complex subunit antibody, VPS52 GARP complex subunit antibody, vacuolar protein sorting 52 homolog (S. cerevisiae) antibody, VPS52 antibody, Vps52 antibody, vps52 antibody

Background: Synonyms:ARE1, dJ1033B10.5, DKFZp547I194, RP5 1033B10, SAC2, SACM2L, VPS52 Background:Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network(TGN). The GARP complex is required for the maintenance of the cycling of mannose 6-phosphate receptors between the TGN and endosomes, this cycling is necessary for proper lysosomal sorting of acid hydrolases such as CTSD(PubMed:15878329, PubMed:18367545). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor(TFRC) to the plasma membrane(PubMed:25799061).

Molecular Weight: 82 kDa

Gene ID: 6293

UniProt: Q8N1B4