VAC14 antibody

Catalog No. ABIN7120699

Product Details anti-VAC14 Antibody

Target: VAC14 (Vac14 Homolog (VAC14))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAC14 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Vac14 homolog

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:2000,IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for VAC14

Target: VAC14 (Vac14 Homolog (VAC14))

Alternative Name: VAC14 (VAC14 Products)

Background: Synonyms:ArPIKfyve, FLJ10305, FLJ36622, FLJ46582, Protein VAC14 homolog, Tax1 binding protein 2, TAX1BP2, TRX, VAC14, Vac14 homolog(S. cerevisiae) Background:The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate(PtdIns(3,5)P2). Acts as a positive activator of PIKfyve kinase activity. Also required to maintain normal levels of phosphatidylinositol 3-phosphate(PtdIns(3)P) and phosphatidylinositol 5-phosphate(PtdIns(5)P). Plays a role in the biogenesis of endosome carrier vesicles(ECV) / multivesicular bodies(MVB) transport intermediates from early endosomes.

Molecular Weight: 88 kDa,65 kDa

Gene ID: 55697

UniProt: Q08AM6

Pathways: Inositol Metabolic Process