USP14 antibody

Catalog No. ABIN7120498

Product Details anti-USP14 Antibody

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin specific peptidase 14(tRNA-guanine transglycosylase)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Alternative Name: USP14 (USP14 Products)

Synonyms: TGT antibody, DDBDRAFT_0202821 antibody, DDBDRAFT_0237695 antibody, DDB_0202821 antibody, DDB_0237695 antibody, 2610005K12Rik antibody, 2610037B11Rik antibody, AW107924 antibody, C78769 antibody, ax antibody, zgc:55949 antibody, wu:fk63d09 antibody, MGC81945 antibody, tgt antibody, MGC69343 antibody, USP14 antibody, ubiquitin specific peptidase 14 antibody, peptidase C19 family protein antibody, ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) antibody, ubiquitin specific protease 14 antibody, ubiquitin specific peptidase 14 S homeolog antibody, universal stress protein antibody, Ubiquitin carboxyl-terminal hydrolase 14 antibody, USP14 antibody, usp14 antibody, Usp14 antibody, Bm1_28765 antibody, usp14.S antibody, RR_RS06480 antibody, usp-14 antibody

Background: Synonyms:Deubiquitinating enzyme 14, TGT, Ubiquitin thiolesterase 14, USP14 Background:Proteasome-associated deubiquitinase which releases ubiquitin from the proteasome targeted ubiquitinated proteins. Ensures the regeneration of ubiquitin at the proteasome. Is a reversibly associated subunit of the proteasome and a large fraction of proteasome-free protein exists within the cell. Required for the degradation of the chemokine receptor CXCR4 which is critical for CXCL12-induced cell chemotaxis. Serves also as a physiological inhibitor of endoplasmic reticulum-associated degradation(ERAD) under the non-stressed condition by inhibiting the degradation of unfolded endoplasmic reticulum proteins via interaction with ERN1. Indispensable for synaptic development and function at neuromuscular junctions(NMJs).

Molecular Weight: 52-60 kDa

Gene ID: 9097

UniProt: P54578