UBR2 antibody
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- Target See all UBR2 Antibodies
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This UBR2 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- ubiquitin protein ligase E3 component n-recognin 2
- Isotype
- IgG
- Top Product
- Discover our top product UBR2 Primary Antibody
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anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibody
UBR2 Reactivity: Human WB, ELISA, IF, RNAi Host: Mouse Monoclonal 4G4 unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 Reactivity: Human, Mouse WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 101-439) antibodyUBR2 Reactivity: Human WB, ELISA Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) antibodyUBR2 Reactivity: Human, Mouse ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (Internal Region) antibodyVerified UBR2 Reactivity: Human ELISA, IHC Host: Goat Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-100) antibodyUBR2 Reactivity: Human WB, ELISA Host: Mouse Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 Reactivity: Human, Horse, Rabbit WB Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (AA 1-439) antibodyUBR2 Reactivity: Human IP Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
anti-Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) antibodyUBR2 Reactivity: Human, Mouse, Rat, Horse, Cow, Dog, Rabbit, Guinea Pig, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:200-1:2000, IF:1:10-1:100, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- Alternative Name
- UBR2 (UBR2 Products)
- Synonyms
- ba49a4.1 antibody, si:ch211-239i4.2 antibody, C6orf133 antibody, RP3-392M17.3 antibody, bA49A4.1 antibody, dJ242G1.1 antibody, dJ392M17.3 antibody, 9930021A08Rik antibody, AI462103 antibody, AW540746 antibody, E130209G04Rik antibody, mKIAA0349 antibody, ubiquitin protein ligase E3 component n-recognin 2 antibody, ubiquitin protein ligase E3 component n-recognin 2 S homeolog antibody, UBR2 antibody, ubr2 antibody, ubr2.S antibody, Ubr2 antibody
- Background
- Synonyms:BA49A4.1, C6orf133, dJ242G1.1, dJ392M17.3, DKFZp686C08114, KIAA0349, N recognin 2, RP3 392M17.3, UBR2 Background:E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.
- Molecular Weight
- 66 kDa
- Gene ID
- 23304
- UniProt
- Q8IWV8
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