UFD1L antibody

Catalog No. ABIN7120482

Product Details anti-UFD1L Antibody

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UFD1L antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: ubiquitin fusion degradation 1 like (yeast)

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for UFD1L

Target: UFD1L (Ubiquitin Fusion Degradation Protein 1 Homolog (UFD1L))

Alternative Name: UFD1L (UFD1L Products)

Synonyms: UFD1 antibody, Ufd1 antibody, ufd1 antibody, wu:fc55f04 antibody, zgc:92341 antibody, Ufd1l antibody, ubiquitin recognition factor in ER associated degradation 1 antibody, ubiquitin recognition factor in ER-associated degradation 1 antibody, ubiquitin fusion degradation 1 like (yeast) antibody, ubiquitin recognition factor in ER associated degradation 1 S homeolog antibody, ubiquitin fusion degradation protein 1 homolog antibody, Ubiquitin Fusion Degradation (yeast UFD homolog) antibody, UFD1 antibody, Ufd1 antibody, UFD1L antibody, ufd1.S antibody, ufd1l antibody, ufd1 antibody, EHI_125920 antibody, LOC100166745 antibody, LOC100635687 antibody, LOC100648660 antibody, ufd-1 antibody

Background: Synonyms:UB fusion protein 1, UFD1, UFD1L Background:The protein encoded by this gene forms a complex with two other proteins, nuclear protein localization-4 and valosin-containing protein, and this complex is necessary for the degradation of ubiquitinated proteins. In addition, this complex controls the disassembly of the mitotic spindle and the formation of a closed nuclear envelope after mitosis. Mutations in this gene have been associated with Catch 22 syndrome as well as cardiac and craniofacial defects. Alternative splicing results in multiple transcript variants encoding different isoforms. A related pseudogene has been identified on chromosome 18.

Molecular Weight: 37 kDa

Gene ID: 7353

UniProt: Q92890