TRIM32 antibody

Catalog No. ABIN7120284

Product Details anti-TRIM32 Antibody

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM32 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: tripartite motif-containing 32

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TRIM32

Target: TRIM32 (Tripartite Motif Containing 32 (TRIM32))

Alternative Name: TRIM32 (TRIM32 Products)

Synonyms: BBS11 antibody, HT2A antibody, LGMD2H antibody, TATIP antibody, 1810045E12Rik antibody, 3f3 antibody, Zfp117 antibody, tripartite motif containing 32 antibody, tripartite motif-containing 32 antibody, TRIM32 antibody, trim32 antibody, Trim32 antibody

Background: Synonyms:72 kDa Tat interacting protein, BBS11, HT2A, LGMD2H, TATIP, TRIM32, tripartite motif containing 32, Zinc finger protein HT2A Background:Has an E3 ubiquitin ligase activity. Ubiquitinates DTNBP1(dysbindin) and promotes its degradation. May ubiquitinate BBS2. May play a significant role in mediating the biological activity of the HIV-1 Tat protein in vivo. Binds specifically to the activation domain of HIV-1 Tat and can also interact with the HIV-2 and EIAV Tat proteins in vivo.

Molecular Weight: 65-72 kDa

Gene ID: 22954

UniProt: Q13049

Pathways: Negative Regulation of intrinsic apoptotic Signaling