TFEC antibody

Catalog No. ABIN7120076

The Rabbit Polyclonal anti-TFEC antibody is suitable to detect TFEC in samples from Human, Mouse and Rat. It has been validated for ELISA, WB, IHC and IP.

Quick Overview for TFEC antibody (ABIN7120076)

Target: TFEC (Transcription Factor EC (TFEC))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFEC antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Product Details anti-TFEC Antibody

Purpose: TFEC antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: transcription factor EC

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IP: 1:200-1:1000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for TFEC

Target: TFEC (Transcription Factor EC (TFEC))

Alternative Name: TFEC

Background:

Synonyms: Transcription factor EC (TFE-C)|Class E basic helix-loop-helix protein 34 (bHLHe34)|Transcription factor EC-like (hTFEC-L)|TFEC|BHLHE34|TCFEC|TFECL

Background: Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F(that includes an E-box sequence). Binds to element F in an E-box sequence-specific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrate-resistant acid phosphatase(TRAP) E-box containing promoter(By similarity). Collaborates with MITF in target gene activation(By similarity). Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence(By similarity). Binds to mu E3 DNA sequence of the immunoglobulin heavy-chain gene enhancer(By similarity). Binds DNA in a homo-or heterodimeric form.

Molecular Weight: 65 kDa

Gene ID: 22797

UniProt: O14948