TRAPPC3 antibody

Catalog No. ABIN7120035

Product Details anti-TRAPPC3 Antibody

Target: TRAPPC3 (Trafficking Protein Particle Complex 3 (TRAPPC3))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAPPC3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: trafficking protein particle complex 3

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TRAPPC3

Target: TRAPPC3 (Trafficking Protein Particle Complex 3 (TRAPPC3))

Alternative Name: TRAPPC3 (TRAPPC3 Products)

Synonyms: BET3 antibody, 1110058K12Rik antibody, AI835942 antibody, AU019197 antibody, Bet3 antibody, trafficking protein particle complex 3 antibody, TRAPPC3 antibody, Trappc3 antibody

Background: Synonyms:BET3, BET3 homolog, TRAPPC3 Background:TRAPPC3(trafficking protein particle complex 3, also known as Bet3) is a component of TRAPP, a complex involved in the tethering of transport vesicles to the cis-Golgi membrane. There are three TRAPP complexes identified in yeast with distinct roles: TRAPPI in ER-Golgi traffic, TRAPPII in intra-Golgi and endosome-Golgi traffic, and TRAPPIII in autophagy. Recently it has been proposed that at least two complexes exist in mammals. TRAPPC3 is the most conserved subunit of TRAPP and has been used to precipitate the intact tethering complex both from yeast and from human cells. It has also been reported that TRAPPC3 is required for Rabin8 centrosome trafficking and ciliogenesis. Expressed ubiquitously, TRAPPC3 protein is present in both membrane-bound and cytosolic forms. This antibody recognizes the endogenous 20-22 kDa TRAPPC3 in multiple cell lines.(15728249, 21273506, 23394947)

Molecular Weight: 20 kDa, 30 kDa

Gene ID: 27095

UniProt: O43617