TRIAP1 antibody

Catalog No. ABIN7120027

Product Details anti-TRIAP1 Antibody

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIAP1 antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: TP53 regulated inhibitor of apoptosis 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for TRIAP1

Target: TRIAP1 (TP53 Regulated Inhibitor of Apoptosis 1 (TRIAP1))

Alternative Name: TRIAP1 (TRIAP1 Products)

Synonyms: MDM35 antibody, P53CSV antibody, WF-1 antibody, 1810015M01Rik antibody, AU020874 antibody, AU043831 antibody, P53csv antibody, Wf-1 antibody, p53csv-A antibody, triap1 antibody, triap1a antibody, p53csv-B antibody, triap1-a antibody, triap1-b antibody, triap1b antibody, zgc:112025 antibody, TP53 regulated inhibitor of apoptosis 1 antibody, TP53 regulated inhibitor of apoptosis 1 S homeolog antibody, TP53 regulated inhibitor of apoptosis 1 L homeolog antibody, TRIAP1 antibody, Triap1 antibody, triap1.S antibody, triap1.L antibody, triap1 antibody

Background: Synonyms:15E1.1, HSPC132, P53CSV, Protein 15E1.1, TRIAP1, WF 1 Background:Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin(CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid(PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane(PubMed:23931759). Likewise, the TRIAP1:PRELID3A complex mediates the transfer of phosphatidic acid(PA) between liposomes(in vitro) and probably functions as a PA transporter across the mitochondrion intermembrane space(in vivo)(PubMed:26071602). Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis(PubMed:15735003).

Molecular Weight: 32 kDa

Gene ID: 51499

UniProt: O43715

Pathways: Negative Regulation of intrinsic apoptotic Signaling