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THOC6 antibody

THOC6 Reactivity: Human, Mouse, Rat WB, ELISA, IHC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7119928
  • Target See all THOC6 Antibodies
    THOC6 (THO Complex 6 Homolog (THOC6))
    Reactivity
    • 32
    • 16
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 27
    • 5
    Rabbit
    Clonality
    • 29
    • 3
    Polyclonal
    Conjugate
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This THOC6 antibody is un-conjugated
    Application
    • 22
    • 20
    • 3
    • 3
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    THO complex 6 homolog(Drosophila)
    Isotype
    IgG
    Top Product
    Discover our top product THOC6 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    THOC6 (THO Complex 6 Homolog (THOC6))
    Alternative Name
    THOC6 (THOC6 Products)
    Synonyms
    WDR58 antibody, fSAP35 antibody, F830014G06Rik antibody, Wdr58 antibody, Pdrp antibody, zgc:101618 antibody, thoc6 antibody, THO complex 6 antibody, THO complex 6 homolog (Drosophila) antibody, THO complex 6 L homeolog antibody, THOC6 antibody, Thoc6 antibody, thoc6 antibody, thoc6.L antibody
    Background
    Synonyms:WDR58 Background:Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.
    Molecular Weight
    35 kDa
    Gene ID
    79228
    UniProt
    Q86W42
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