THOC6 antibody

Catalog No. ABIN7119928

Product Details anti-THOC6 Antibody

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This THOC6 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: THO complex 6 homolog(Drosophila)

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for THOC6

Target: THOC6 (THO Complex 6 Homolog (THOC6))

Alternative Name: THOC6 (THOC6 Products)

Synonyms: WDR58 antibody, fSAP35 antibody, F830014G06Rik antibody, Wdr58 antibody, Pdrp antibody, zgc:101618 antibody, thoc6 antibody, THO complex 6 antibody, THO complex 6 homolog (Drosophila) antibody, THO complex 6 L homeolog antibody, THOC6 antibody, Thoc6 antibody, thoc6 antibody, thoc6.L antibody

Background: Synonyms:WDR58 Background:Acts as component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex(EJC) and is recruited in a splicing-and cap-dependent manner to a region near the 5' end of the mRNA where it functions in mRNA export to the cytoplasm via the TAP/NFX1 pathway. The TREX complex is essential for the export of Kaposi's sarcoma-associated herpesvirus(KSHV) intronless mRNAs and infectious virus production. Plays a role in apoptosis negative control involved in brain development.

Molecular Weight: 35 kDa

Gene ID: 79228

UniProt: Q86W42