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TBC1D17 antibody
TBC1D17
Reactivity: Human, Rat, Mouse
WB, ELISA, IHC, IF
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-TBC1D17 Antibody
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Target
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TBC1D17
(TBC1 Domain Family, Member 17 (TBC1D17))
Reactivity
All reactivities for TBC1D17 antibodies
Human, Rat, Mouse
Host
All hosts for TBC1D17 antibodies
Rabbit
Clonality
All clonalities for TBC1D17 antibodies
Polyclonal
Conjugate
All conjugates for TBC1D17 antibodies
This TBC1D17 antibody is un-conjugated
Application
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
Purification
Immunogen affinity purified
Purity
≥95 % as determined by SDS-PAGE
Immunogen
TBC1 domain family, member 17
Isotype
IgG
Alternatives
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Application Details
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Application Notes
WB: 1:500-1:2000, IHC: 1:20-1:200, IF: 1:20-1:200
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
-20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Expiry Date
12 months
Target Details for TBC1D17
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Target
TBC1D17
(TBC1 Domain Family, Member 17 (TBC1D17))
Alternative Name
TBC1D17 (TBC1D17 Products )
Background
Synonyms: Background:Probable GTPase-activating protein for Rab8, its transient association with Rab8 is mediated by OPTN. Inhibits Rab8-mediated endocytic trafficking, such as of transferrin receptor(TfR) and reduces Rab8 recruitnment to tubules emanating from the endocytic recycling compartment(ERC). Involved in regulation of autophagy. Mediates inhibition of autophagy caused by the OPTN variant GLC1E LYS-50, the function requires its catalytic activity, however, the involved Rab is not known.
Molecular Weight
73 kDa
Gene ID
79735
UniProt
Q9HA65
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