SIKE1 antibody

Catalog No. ABIN7119610

Product Details anti-SIKE1 Antibody

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SIKE1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: suppressor of IKK epsilon

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SIKE1

Target: SIKE1 (Suppressor of IKBKE 1 (SIKE1))

Alternative Name: SIKE1 (SIKE1 Products)

Synonyms: SIKE antibody, 2810005O12Rik antibody, 5730470L24Rik antibody, AI450236 antibody, AI839862 antibody, Sike antibody, Sikeb antibody, RGD1311316 antibody, suppressor of IKBKE 1 antibody, SIKE1 antibody, Sike1 antibody

Background: Synonyms:SIKE Background:Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus-and TLR3-triggered IRF3. Inhibits TLR3-mediated activation of interferon-stimulated response elements(ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways.

Molecular Weight: 24 kDa

Gene ID: 80143

UniProt: Q9BRV8