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SOCS6 antibody

SOCS6 Reactivity: Human, Mouse, Rat WB, IHC, ELISA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7119606
  • Target See all SOCS6 Antibodies
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Reactivity
    Human, Mouse, Rat
    Host
    • 45
    • 3
    • 1
    Rabbit
    Clonality
    • 48
    • 1
    Polyclonal
    Conjugate
    • 18
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SOCS6 antibody is un-conjugated
    Application
    • 38
    • 21
    • 20
    • 13
    • 13
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Purification
    Immunogen affinity purified
    Purity
    ≥95 % as determined by SDS-PAGE
    Immunogen
    suppressor of cytokine signaling 6
    Isotype
    IgG
    Top Product
    Discover our top product SOCS6 Primary Antibody
  • Application Notes
    WB: 1:500-1:2000, IHC: 1:20-1:200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
    Expiry Date
    12 months
  • Target
    SOCS6 (Suppressor of Cytokine Signaling 6 (SOCS6))
    Alternative Name
    SOCS6 (SOCS6 Products)
    Synonyms
    CIS-4 antibody, CIS4 antibody, HSPC060 antibody, SOCS-4 antibody, SOCS-6 antibody, SOCS4 antibody, SSI4 antibody, STAI4 antibody, STATI4 antibody, socs6 antibody, MGC81477 antibody, SOCS6 antibody, 1500012M23Rik antibody, 5830401B18Rik antibody, AI447482 antibody, Cis4 antibody, Cish4 antibody, Socs4 antibody, socs6l antibody, zgc:64107 antibody, wu:fb77f06 antibody, suppressor of cytokine signaling 6 antibody, suppressor of cytokine signaling 6 L homeolog antibody, suppressor of cytokine signaling antibody, suppressor of cytokine signaling 6b antibody, SOCS6 antibody, Socs6 antibody, socs6.L antibody, socs6 antibody, socs6b antibody
    Background
    Synonyms:CIS4, SOCS4 Background:SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. May be a substrate recognition component of a SCF-like ECS(Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins(By similarity). Regulates KIT degradation by ubiquitination of the tyrosine-phosphorylated receptor.
    Molecular Weight
    70 kDa
    Gene ID
    9306
    UniProt
    O14544
    Pathways
    JAK-STAT Signaling, Carbohydrate Homeostasis
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