SF3B3 antibody

Catalog No. ABIN7119436

Product Details anti-SF3B3 Antibody

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SF3B3 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: splicing factor 3b, subunit 3, 130kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3 ,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SF3B3

Target: SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))

Alternative Name: SF3B3 (SF3B3 Products)

Synonyms: GB11574 antibody, rse1 antibody, sap130 antibody, sf3b130 antibody, staf130 antibody, sf3b3 antibody, 1810061H24Rik antibody, 5730409A01Rik antibody, AA409318 antibody, D8Ertd633e antibody, RSE1 antibody, SAP130 antibody, mKIAA0017 antibody, ik:tdsubc_2b2 antibody, wu:fb81f05 antibody, xx:tdsubc_2b2 antibody, zgc:55440 antibody, SF3b130 antibody, STAF130 antibody, splicing factor 3b subunit 3 antibody, splicing factor 3B subunit 3 antibody, splicing factor 3b, subunit 3, 130kDa antibody, splicing factor 3b subunit 3 L homeolog antibody, splicing factor 3b, subunit 3 antibody, SF3B3 antibody, LOC550935 antibody, sf3b3 antibody, Sf3b3 antibody, LOC100178056 antibody, sf3b3.L antibody

Background: Synonyms:KIAA0017, SAP130 Background:This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.

Molecular Weight: 140 kDa

Gene ID: 23450

UniProt: Q15393