SOS1 antibody

Catalog No. ABIN7119340

Product Details anti-SOS1 Antibody

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SOS1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: son of sevenless homolog 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500 - 1:2000, IF: 1:50 - 1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SOS1

Target: SOS1 (Son of Sevenless Homolog 1 (SOS1))

Alternative Name: SOS1 (SOS1 Products)

Synonyms: GF1 antibody, GGF1 antibody, GINGF antibody, HGF antibody, NS4 antibody, 4430401P03Rik antibody, 9630010N06 antibody, AI449023 antibody, SOS Ras/Rac guanine nucleotide exchange factor 1 antibody, son of sevenless homolog 1 (Drosophila) antibody, SOS1 antibody, Sos1 antibody

Target Type: Viral Protein

Background: Synonyms:SOS1, GF1, GGF1, GINGF, HGF, NS4, son of sevenless homolog 1 Background:Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).

Molecular Weight: 180 kDa

Gene ID: 6654

UniProt: Q07889

Pathways: RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Hepatitis C, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling