SMCR7L antibody

Catalog No. ABIN7119193

Product Details anti-SMCR7L Antibody

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SMCR7L antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: Smith-Magenis syndrome chromosome region, candidate 7-like

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:500-1:5000, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SMCR7L

Target: SMCR7L (Smith-Magenis Syndrome Chromosome Region, Candidate 7-Like (SMCR7L))

Alternative Name: SMCR7L (SMCR7L Products)

Synonyms: MGC115280 antibody, HSU79252 antibody, MID51 antibody, MIEF1 antibody, dJ1104E15.3 antibody, A230016E22 antibody, AI452372 antibody, im:7156228 antibody, smcr7l antibody, zgc:162279 antibody, mitochondrial elongation factor 1 antibody, mitochondrial elongation factor 1 S homeolog antibody, MIEF1 antibody, mief1.S antibody, Mief1 antibody, mief1 antibody

Background: Synonyms:dJ1104E15.3, FLJ20232, HSU79252, MID51, MIEF1, SMCR7L Background:Human SMCR7L gene encodes, MID51, the mitochondrial dynamic protein of 51 kDa(also called mitochondrial elongation factor 1, MIEF1). MID51 is a single-pass membrane protein anchored to the mitochondrial outer membrane and regulates mitochondrial morphology. Mitochondrial morphology is controlled by two opposing processes: fusion and fission. Elevated MID51 levels induce extensive mitochondrial fusion, whereas depletion of MID51 causes mitochondrial fragmentation. MID51 interacts with and recruits Drp1 to mitochondria, suggesting a critical role of MID51 in regulation of mitochondrial fusion-fission machinery in vertebrates.

Molecular Weight: 49 kDa

UniProt: Q9NQG6