SPPL2A antibody

Catalog No. ABIN7119061

Product Details anti-SPPL2A Antibody

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPPL2A antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: signal peptide peptidase-like 2A

Isotype: IgG

Application Details

Application Notes: WB: 1:200-1:2000, IHC: 1:20-1:200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SPPL2A

Target: SPPL2A (Signal Peptide Peptidase-Like 2A (SPPL2A))

Alternative Name: SPPL2A (SPPL2A Products)

Background: Synonyms: Background:SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A(SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273).

Molecular Weight: 58 kDa

UniProt: Q8TCT8