SRRM1 antibody

Catalog No. ABIN7118908

Product Details anti-SRRM1 Antibody

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SRRM1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: serine/arginine repetitive matrix 1

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for SRRM1

Target: SRRM1 (Serine/arginine Repetitive Matrix 1 (SRRM1))

Alternative Name: SRRM1 (SRRM1 Products)

Synonyms: 160-KD antibody, POP101 antibody, SRM160 antibody, AA407769 antibody, Srm160 antibody, serine and arginine repetitive matrix 1 antibody, serine/arginine repetitive matrix 1 antibody, SRRM1 antibody, Srrm1 antibody

Background: Synonyms:SRM160 Background:Part of pre-and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer(ESE)-dependent splicing activation by bridging together sequence-specific(SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP(SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3'-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double-or single-stranded nucleic acid substrates.

Molecular Weight: 120-160 kDa

Gene ID: 10250

UniProt: Q8IYB3