Scinderin antibody

Catalog No. ABIN7118804

Product Details anti-Scinderin Antibody

Target: Scinderin (SCIN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Scinderin antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: scinderin

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:5000, IP: 1:200-1:1000, IHC: 1:20-1:200, IF: 1:10-1:100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for Scinderin

Target: Scinderin (SCIN)

Alternative Name: SCIN (SCIN Products)

Synonyms: MGC81993 antibody, si:ch211-134n17.3 antibody, AW545522 antibody, adseverin antibody, Scind antibody, scinderin L homeolog antibody, scinderin antibody, adseverin antibody, scin.L antibody, SCIN antibody, scin antibody, LOC100496020 antibody, Scin antibody

Background: Synonyms:Adseverin, KIAA1905, SCIN, scinderin Background:Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes(By similarity).

Molecular Weight: 75-80 kDa

Gene ID: 85477

UniProt: Q9Y6U3

Pathways: Regulation of Actin Filament Polymerization