RBM25 antibody
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- Target See all RBM25 Antibodies
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
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Reactivity
- Mouse, Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This RBM25 antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Purification
- Immunogen affinity purified
- Purity
- ≥95 % as determined by SDS-PAGE
- Immunogen
- RNA binding motif protein 25
- Isotype
- IgG
- Top Product
- Discover our top product RBM25 Primary Antibody
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anti-RNA Binding Motif Protein 25 (RBM25) (AA 614-843) antibody
RBM25 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) antibodyRBM25 Reactivity: Mouse, Human IF Host: Rabbit Polyclonal unconjugated
anti-RNA Binding Motif Protein 25 (RBM25) (AA 285-334) antibodyRBM25 Reactivity: Mouse, Human, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio), Chicken, Monkey, Pig, Xenopus laevis WB Host: Rabbit Polyclonal unconjugated
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- Application Notes
- WB: 1:200-1:2000, IP: 1:200-1:2000, IHC: 1:20-1:200
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
- Expiry Date
- 12 months
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- Target
- RBM25 (RNA Binding Motif Protein 25 (RBM25))
- Alternative Name
- RBM25 (RBM25 Products)
- Background
- Synonyms:fSAP94, NET52, Protein S164, RBM25, RED120, RNA binding motif protein 25, RNA binding protein 25, RNPC7, S164 Background:RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site(5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7L3 promotes U1 snRNP binding to a weak 5' ss in a 5'-CGGGCA-3'-dependent manner. Binds to the exonic splicing enhancer 5'-CGGGCA-3' RNA sequence located within exon 2 of the BCL2L1 pre-mRNA. Also involved in the generation of an abnormal and truncated splice form of SCN5A in heart failure.
- Molecular Weight
- 110-120 kDa
- Gene ID
- 58517
- UniProt
- P49756
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