RBM14 antibody

Catalog No. ABIN7118671

Product Details anti-RBM14 Antibody

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RBM14 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: RNA binding motif protein 14

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Expiry Date: 12 months

Target Details for RBM14

Target: RBM14 (RNA Binding Motif Protein 14 (RBM14))

Alternative Name: RBM14 (RBM14 Products)

Synonyms: im:7053198 antibody, wu:fc08a04 antibody, zgc:110682 antibody, sip antibody, coaa antibody, psp2 antibody, sytip1 antibody, tmem137 antibody, MGC52864 antibody, MGC132117 antibody, MGC75876 antibody, RBM14 antibody, RBM4 antibody, COAA antibody, PSP2 antibody, SIP antibody, SYTIP1 antibody, TMEM137 antibody, 1300007E16Rik antibody, Sytip antibody, p16 antibody, p16K antibody, CoAA antibody, rbm14 antibody, zgc:85696 antibody, RNA binding motif protein 14a antibody, RNA binding motif protein 14 L homeolog antibody, RNA binding motif protein 14 antibody, RNA binding motif protein 14b antibody, rbm14a antibody, rbm14.L antibody, rbm14 antibody, RBM14 antibody, Rbm14 antibody, rbm14b antibody

Background: Synonyms:SIP Background:Isoform 1 may function as a nuclear receptor coactivator, enhancing transcription through other coactivators such as NCOA6 and CITED1. Isoform 2, functions as a transcriptional repressor, modulating transcriptional activities of coactivators including isoform 1, NCOA6 and CITED1(PubMed:11443112). Regulates centriole biogenesis by suppressing the formation of aberrant centriolar protein complexes in the cytoplasm and thus preserving mitotic spindle integrity. Prevents the formation of the STIL-CENPJ complex(which can induce the formation of aberrant centriolar protein complexes) by interfering with the interaction of STIL with CENPJ(PubMed:25385835).

Molecular Weight: 70-75 kDa

Gene ID: 10432

UniProt: Q96PK6

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway